Carbapenem-Resistant Enterobacteriaceae (CRE)
Heathcare-Associated Infections
Methicillin-Resistant Staphylococcus aureus (MRSA)
Vancomycin-Intermediate & -Resistant Staphylococcus aureus (VISA/VRSA)
Vancomycin-Resistant Enterococci (VRE)
Antibiotic Resistance & Appropriate Antibiotic Use
Antimicrobial resistance is a substantial threat to public health in the United States. Overuse of antibiotics is a major reason for the current crisis in antimicrobial resistance. For example, approximately 50 percent of upper respiratory tract infections and 80 percent of acute bronchitis are treated with antibiotics, although antibiotics – designed to kill bacteria – have little impact on these predominantly viral illnesses. This has contributed to the alarmingly rapid rise in antibiotic-resistant Streptococcus pneumoniae in North Carolina and throughout the U.S.
Antimicrobial resistance is also a growing problem in long-term care facilities and in hospitals, particularly in intensive care units. Infections caused by drug-resistant microbes result in increased illness and deaths, longer hospital stays, and higher health care expenditures.
Appropriate antibiotic use can prevent or slow the emergence of resistance, prevent illnesses and deaths, and reduce healthcare costs.